My wife loves her some Pat Benatar and 1980 served as her coming out party. The first of two songs on this countdown, this tune has a great bluesy riff followed by a chorus that when it hits, you want to scream it out like she does. She exuded female empowerment in her tracks, and this song is no different. Coming in at #16 of the Top 20 Songs Turning 40 years old is You Better Run by Pat Benatar.